PD-1 and PD-L1

Immunotherapy presents promising results for cancer treatment in the past few years. PD-1, also known as CD279, is a 55-kDa transmembrane protein containing 288 amino acids. First discovered in 1992, PD-1 served as an inhibitor of both innate and adaptive immune responses. Of note, PD-1 is highly expressed on tumor-specific T cells. PD-1 and PD-L1 https://immune-checkpoint.creative-biolabs.com/pd-1-and-pd-l1-pd-l2-pathway.htm